10047
Fluka
Ampicillin
BioChemika, anhydrous, ≥98.0% (NT)
| Synonym: | |
| CAS Number: | 69-53-4 |
| Linear Formula: | C16H19N3O4S |
| Molecular Weight: | 349.40 |
| Beilstein Registry Number: | 1090925 |
| EC Number: | 200-709-7 |
| MDL number: | MFCD00005175 |
Description
| Biochem/physiol Actions | Inhibits cell wall synthesis in Escherichia coli1; In the purification of penicillin acylase2; Enhances luminol chemiluminescence.3 |
| A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
Properties
| product line | BioChemika |
| assay | ≥98.0% (NT) |
| optical activity | [α]20/D +295±5°, c = 0.2% in H2O |
| total impurities | ≤1% water |
| mp | 208 °C (dec.)(lit.) |
| solubility | NH4OH 1 M: 50 mg/mL, clear, colorless |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42/43 |
| Safety Statements | 22-26-36/37 |
| WGK Germany | 2 |
| RTECS | XH8350000 |
Related Products
| Replaced by | A9393, Ampicillin |
References
| Cited Reference | 1. M. Nguyen-Distèche Eur. J. Biochem. 41, 457, (1974) Abstract |
| 2. P.B. Mahajan, P.S. Borkar Appl. Biochem. Biotechnol. 9, 421, (1984) Abstract | |
| 3. D.S. Milbrath Biolumin. Chemilumin., Proc. Int. Biolumin. Chemilumin. Symp. Ed.J.Schoelmerich Chichester, UK 4, 515, (1987) | |
| Merck | Merck 13,591 |
| reference | Corp MSDS 1 (1), 247:A / RegBook 1 (2), 2065:H / Sax 6, 201 / Sigma FT-IR 1 (1), 619:A / Structure Index 1, 328:A:3 |
